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Graphical presentation of CX-5461-mediated activation of the cytosolic DNA sensing pathway. cGAS binding towards the cytosolic DNA activates the secondary messenger 2,3-cGAMP making use of cGAS to be a catalyst. Activated STING buds off the ER moving to your perinuclear Golgi, wherever it is palmitoylated.The photographs or other 3rd party content

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